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In the past few years DNA templated fluorescent
2021-02-10

In the past few years, DNA-templated fluorescent metal nanoparticles have been developed as ideal alternatives to organic dyes due to their facile synthetic process, outstanding optical properties, ultrafine size, and fine biological compatibility. Since the first successful demonstration of DNA-tem
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The early serologic response of
2021-02-10

The early serologic response of infants to infection with HIV-1 is obscured by the presence of transplacentally acquired maternal HIV antibody. However, the HIV hmg-coa reductase inhibitor produced in vitro by peripheral blood from infants has been studied (Pollack et al., 1993) and it has been sho
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Rambabu et al reported A series of
2021-02-10

Rambabu et al. reported A series of novel N-substituted 2-(2-oxo-2H-chromen-4-yloxy)propanamide derivatives synthesized from readily available 4-hydroxy coumarin to the corresponding ethyl 2-(2-oxo-2H-chromen-4-yloxy)propanoate followed by hydrolysis and further reacted with different substituted am
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On top of the hardware ASTS employs Linux
2021-02-10

On top of the hardware, ASTS employs Linux SUSE with High-Availability (HA) Extension: a COTS OS provided with two clustering software (Pacemaker Cluster Resource Manager (CRM) and Corosync) responsible for resources orchestration, failure diagnosis, nodes coordination, and fail-over management. The
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br Introduction The dopaminergic system and
2021-02-10

Introduction The dopaminergic system and its projections including both the prefrontal TNKS 49 (PFC) and striatum are known as being crucial to synaptic plasticity, skill acquisition and higher order functions (e.g., working memory and cognitive control; Matsumoto et al., 2003). Variations in dop
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Many researchers studied the experimental investigation
2021-02-09

Many researchers studied the experimental investigation of RHA in cement enhances the strength and durability of the concrete [9], [10], [11], [12]. It is most important that concrete must withstand its strength even after it is being exposed to any corrosive environment over a period of time. In ad
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The action of pt PGE
2021-02-09

The action of 17-pt-PGE2 as an EP1 receptor agonist [34] was demonstrated in several experimental settings, including cancer, neurons, vascular system, kidney and was confirmed by application of EP1 receptor selective antagonists [35], [36], [37], [38], [39], [40], [41]. Receptor binding studies in
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Although PKC in cancer cells is known
2021-02-09

Although PKCδ in cancer MK-4827 hydrochloride synthesis is known to promote antiapoptotic signaling, a cleaved form of PKCδ, δCF, has been reported to play a contrasting role in enhancing apoptosis (Reyland, 2007), and these complex functions appear to be cell-type dependent (Basu and Pal, 2010). In
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Although DGK is a lipid modulating enzyme the role of
2021-02-09

Although DGKγ is a lipid-modulating enzyme, the role of DGKγ in integral cell metabolism has not been reported. We found that DGKγ made a difference on cell metabolism profile in HCC cells, which may be caused partially by the downregulation of GLUT1. Glucose is a major source of energy, and decreas
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Therefore in this study we determined whether exogenous
2021-02-09

Therefore, in this study we determined whether exogenous LTD, a potent agonist of both CysLT and CysLT receptors , , induces jak inhibitors edema and AQP4 expression in mouse brain; if so, which subtype of the receptors is involved in AQP4 expression in mouse brain and the cultured rat astrocytes.
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We further correlated OPRK and OPRM
2021-02-09

We further correlated OPRK1 and OPRM1 methylation levels with individual characteristics in Xinjiang Han and Uygur controls. Partial correlation analyses showed that OPRK1 methylation was positively correlated with age in Uygur male controls (r=0.72, p=0.001, adjusted by body mass index (BMI), gluco
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Cardiogenesis is enhanced with timely
2021-02-09

Cardiogenesis is enhanced with timely application of Wnt pathway activators and inhibitors. A combination of Wnt/β-catenin signaling pathway activators such as CHIR99021 and inhibitors such as IWP-2 and IWR-1 have been found to be highly efficient cardiomyocyte differentiation protocols [27], [28].
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br Methods br Results IAA
2021-02-09

Methods Results IAA-94 abrogated the protective effects of IPC as it increased myocardial infarction (MI) due to IR injury in vitro (Diaz et al., 1999), and also prevented cyclosporine A mediated cardioprotection (Diaz et al., 2013). Moreover, IAA-94-sensitive currents were observed in cardiac
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Building s constructional elements should be able to protect
2021-02-09

Building's constructional elements should be able to protect residents from the negative effect of noise caused by surroundings [19]. The World Health Organization estimates that each year more than one million Healthy Life Years are lost in the European Union member states and other Western Europea
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ROS generation is crucial for NETs release upon
2021-02-09

ROS generation is crucial for NETs release upon both physiological or pathogenic stimuli [16,30]. In our study, we further verified this conclusion by demonstrating that SRA stimulation by Poly I enhanced intracellular ROS levels while scavenging of ROS by anti-oxidant agents effectively abolished t
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